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These results should be interpreted with a qualified healthcare providerthey help contextualize expected response patterns but do not predict exact medication response or guarantee freedom from side effects
In particular, the SURMOUNT-1 trial demonstrated that patients on tirzepatide experienced up to 22.5% weight loss , while semaglutide users typically averaged around 15% at the highest dose
Neither medication is clearly better or worse for fatigue in all cases
Ipamorelin largely avoids these issues
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